November 29th , 2017
14h30 to 17h
SUCCESSFUL INTERNATIONAL EXPERIENCES IN CLINICAL RESEARCH: LESSONS FOR EMERGING ECONOMIES
According to the data available on the website ClinicalTrials.gov, the United States of America is responsible for the majority of the ongoing clinical trials in the world, followed by China and France, the number one in Europe regarding the number of clinical trials. Learning about successful international experiences is essential to contribute to the development of researches conducted within networks as well as multicenter clinical trials. The panel aims to promote the debate about international experiences in clinical research that can inspire and help research institutions to overcome challenges and to establish partnerships.
Moderator: Alexandre Biasi (Hospital do Coração) - BRAZIL
1) The experience of the VIPER Institute in multicenter clinical trials
Speaker: Leslie Victoria Boyer (University of Arizona) – UNITED STATES
2) Development of clinical studies at the NIH / USA: contributions to Brazil
Speaker: Phillip Scheinberg (Hospital Beneficência Portuguesa de São Paulo) - BRAZIL
3) The French experience in clinical research: the Pôle Recherche Clinique
Speaker: Claire Levy-Marchal (Institut National de la Santé et de la Recherche Médicale) - FRENCH
NEW THERAPEUTIC APPROACHES IN CELLULAR AND MOLECULAR IMMUNOLOGY
Chronic diseases, especially autoimmune and cancerous diseases, are a priority in the search for new therapeutic solutions that are promising and safer for patients. In this sense, we seek to present and discuss new therapeutic approaches for these clinical conditions, as well as the mechanisms of immune system regulation, immunotherapy and nanotherapy in drug delivery.
Moderator: Leonilda Maria Barbosa dos Santos (Universidade Estadual de Campinas) - BRAZIL
1) Treg IL-2R as a target for the immunotherapy of autoimmunity
Speaker: C. Garrison Fathman (Stanford Medical School e Department of Chemistry) – UNITED STATES
2) The role of the Regulatory T Cells in Health and Disease
Palestrante: Robert Negrin (Stanford Medical School e Department of Chemistry) – UNITED STATES
3) Discovery of nitric oxide and cyclic GMP in cell signaling and their role in drug development
Speaker: Ferid Murad (Stanford Medical School e Department of Chemistry) – UNITED STATES
Mata Atlântica Room
CHALLENGES OF POPULATION AGING
WHO believes that promoting active aging is a way to mitigate the risk of breaking social and health systems, as active and healthy seniors contribute to society and consume fewer resources. Aging in Brazil and in other developing countries is a concern of the Health and Social Welfare System, especially because aging in these countries has been very fast in comparison to what has been observed in developed countries. Given the relevance of the theme and recognizing that it is essential to discuss the new challenges in elderly population care and the economic impact of the aging process, the panel intends to discuss and evaluate the economic and health impact of aging in Brazil and in the world.
Speaker: Yeda Duarte (Universidade de São Paulo) - BRAZIL
1) The longevity revolution
Speaker: Ina Voelcker (Centro Internacional de Longevidade Brasil) - BRAZIL
2) Economic Impact of Aging
Speaker: Kaizo Iwakami Beltrão (Fundação Getúlio Vargas) - BRAZIL
3) Aging and health
Speaker: Márcia Carrera Campos Leal (Universidade Federal de Pernambuco) – BRAZIL
ARBOVIRUSES SCENARIO TWO YEARS AFTER THE ZIKA EMERGENCY
In 2015 and 2016, Brazil was severely affected by the congenital syndrome associated with zika virus infection that affected thousands of families, especially pregnant women and babies with congenital abnormalities. In addition, chikungunya was responsible for 196 fatalities in 2016, causing surprise to health managers and the scientific community, as it was considered a disease with low mortality in other countries. The Brazilian government declared a Public Health Emergency of National Importance in November 2015, due to the change in the pattern of cases of microcephaly. The Ministry of Health then established the National Plan to Combat Aedes and its Consequences. The National Plan contains three broad areas related to care; mobilization and vector combat; and technological development, education and research. Regarding research on arbovirus, more than R$ 250 million were invested.
Moderator: Pedro Vasconcellos (Instituto Evandro Chagas) - BRAZIL
1) Emerging Arboviruses: challenges to public health
Palestrante: Van-Mai Cao-Lormeau (Institut Louis Malardé) – FRENCH POLYNESIAN
2) Congenital abnormalities related to Zika and STORCH
Speaker: Vanessa Van Der Linden (Universidade Federal de Pernambuco) - BRAZIL
3) Economic impact of Chikungunya in Brazil
Speaker: André Siqueira (Instituto Nacional de Infectologia, Fiocruz) - BRAZIL
14h30 to 17h
FROM RESEARCH TO THE DEVELOPMENT OF HEALTH TECHNOLOGIES: INNOVATIONS IN TRANSLATIONAL RESEARCH IN THE WORLD AND BRAZILIAN EXPERIENCES
The development of translational research is still a challenge for Brazil. The promotion of cooperation between countries can accelerate the discovery, development and dissemination of new health interventions. National examples of innovation in this area are the anti-apical serum for the bee Apis melífera sting, the fibrin sealant that has as its raw material the rattlesnake venom and the use of photodynamic therapy to treat cervical cancerous lesions. In this sense, this panel aims to promote the exchange of experiences among national and international research groups, highlighting the current situation of translational research in the world and in Brazil.
Moderator: Jorge Guimarães (Empresa Brasileira de Pesquisa e Inovação Industrial) - BRAZIL
1) Translational Research Programs in the USA
Speaker: Amy Dubois (United States Embassy) - UNITED STATES
2) Translational Research on Phytotherapy
Speaker: João Batista Calixto (Centro de Inovação e Ensaios Pré-Clínicos) - BRAZIL
3) Development of Products in Health 100% national: the experience of UNESP/Botucatu on Translational Research
Speaker: Rui Seabra (Universidade Estadual Paulista) - BRAZIL
4) Translational Research on Photodynamic Therapy
Palestrante: Vanderlei Salvador Bagnato (Universidade de São Paulo) - BRAZIL
RESISTANCE TO ANTIMICROBIALS: WHAT IS THE FUTURE SCENARIO?
Antimicrobial Resistance (AMR) is considered to be one of the major problems in global health, since its increased prevalence poses threats to human, animal and environmental health. In this scenario, the World Health Organization (WHO) published in 2015 the Global Action Plan for AMR and encouraged all its member countries to develop their national action plans. In Brazil, the Ministry of Health, through Decree GM/MS No. 2,775 of December 22, 2016, the committee responsible for designing and conducting the health sector component of the National Action Plan for Prevention and Control of Antimicrobial Resistance (CIPAN). The National Health Surveillance Agency (ANVISA), the Ministry of Agriculture, Livestock and Supply (MAPA), the Ministry of Science, Technology, Innovation and Communications (MCTIC) and the Ministry of Environment (MMA) also participates on the formulation of the plan.
The plan aims to ensure the continuity, as long as possible, of the success of the treatment and prevention of infectious diseases, with guaranteed quality, safe and effective medicines, which are used in a responsible manner and that are also accessible to everyone who needs it.
Thus, given the importance of the theme and its impact on health and the world economy, this panel aims to discuss the future actions toward antimicrobial resistance.
Moderator: Flávia Caselli Pacheco (MINISTÉRIO DA SAÚDE) - BRAZIL
1) The economic impact of antimicrobial resistance
Speaker: Jeremy Knox (Wellcome Trust) – UNITED KINGDOM
2) The impact of antimicrobial resistance in Brazil
Speaker: Ana Cristina Gales (Universidade Federal de São Paulo)
3) Infections related to health care in Brazilian hospitals and the evaluation of antimicrobial use standards and policies
Speaker: Antônio Carlos Campos Pignatari (Universidade Federal de São Paulo) - BRAZIL
Mata Atlântica Room
GENETIC EDITING AND ADVANCED CELL THERAPIES AND THEIR PROMISING HEALTH APPLICABILITY
Genetic editing allows scientists to modify genomes with accuracy, efficiency and flexibility. The aim of the panel is to present the multiple approaches and future perspectives for the treatment of diseases through genetic editing techniques and cell therapies.
Moderator: Mônica Ryff Moreira Roca Vianna (Pontifícia Universidade Católica do Rio Grande do Sul) - BRAZIL
1) Bioethical considerations of the use of genomic edition and cellular therapy
Speaker: Søren Holm (Manchester University) – UNITED KINGDOM
2) Immunotherapy with NK cells
Speaker: Lúcia Mariano da Rocha Silla (Hospital de Clínicas de Porto Alegre) – BRAZIL
3) CART-CELL perspective for the treatment of hematological diseases
Speaker: Martin Hernan Bonamino (Instituto Nacional do Câncer) - BRAZIL
DISRUPTIVE TECHNOLOGIES IN HEALTH - THE CHALLENGE OF CONNECTING PROGRESS AND ACCESSIBILITY
Disruptive technology or disruptive innovation is a term that describes technological innovation, product, or service, which uses a "disruptive" or revolutionary strategy rather than an evolutionary strategy, in order to overcome a prevailing dominant technology in the market. The most disruptive innovations are a minority compared to other innovations introduced in the market.
Disruptive health care technology can be defined as a type of innovation that creates new networks and new organizational cultures involving new actors, with potential to improve health outcomes and the value of health care. This type of innovation alters the systems and the former ways of action in the area.
The objective of this panel is to know which are the disruptive technologies in the health area and to discuss how to reduce the gap between them and their access by the population.
Moderator: Guilherme Rabello (InovaInCor) - BRAZIL
1) Disruptive Technologies in Diagnostic Medicine
Speaker: Roberto Ribeiro da Cruz (Pixeon) - BRAZIL
2) Artificial Intelligence and Health
Speaker: Eduardo Cipriani (IBM Watson Health) - BRAZIL
INTERNACIONALIZAÇÃO DO FOMENTO À PESQUISA EM SAÚDE
National and international scientific cooperation actions with institutions of excellence, promote, encourage and strengthen the development of health researches in the country, in order to meet the needs of public health and the priorities of the National Health System (SUS). These partnerships increase the capacity of the Department of Science and Technology of the Secretariat of Science, Technology and Strategic Inputs of the Ministry of Health (Decit/SCTIE/MS) to invest in the development of health research, bringing new resources and enabling an expansion of actions. In this sense, NIH, Bill & Melinda Gates Foundation and the Newton Fund are important partners of the Ministry of Health and of other Brazilian institutions. The objective of this panel is to show the participants of the event other opportunities to raise funds for the development of research in the country, as well as to present how these agencies promote research around the world.
Moderator: Marcelo Morales (Conselho Nacional de Desenvolvimento Científico e Tecnológico) - BRAZIL
1) Transnational Translation of Knowledge in Research: Cancer Communications Perspective
Speaker: Nelvis Castro (National Institutes of Health) – UNITED STATES
2) The Bill & Melinda Gates Foundation and fundraising to solving global health problems
Speaker: Alexandre Menezes (Consultant, Bill & Melinda Gates Foundation) – BRAZIL
3) Collaborative Research and Innovation in Health: The Newton Fund Experience
Speaker: Rui Lopes (Newton Fund) - BRAZIL
FROM SCIENCE TO POLICY: PROMOTING HEALTH DECISION-MAKING
In 2005, the 58ª World Health Assembly highlighted the need for Member States to establish or strengthen mechanisms for knowledge translation to support public health, health care systems and health-related policies informed by scientific evidence. However, given the multifactorial nature of the policy making process associated with the gap between 'know' and 'do', the panel's proposal is to address the challenge of linking the evidence to health policies as part of the knowledge management process in Science and Technology in Health.
Moderator: Marcus Tolentino (Universidade Federal do Amazonas e Universidade Federal de Sorocaba) - BRAZIL
1) Evidence-Informed Policies: How to Move Forward in a Complex World?
Speaker: Kaelan Moat (Mc Master University) - CANADA
2) Priorities of Scientific Evidences: production versus needs
Speaker: Anne Andermann (McGill University) - CANADA
3) Implementation Research to Improve Health Policies and Programs.
Speaker: Ludovic Reveiz (Organização Pan-Americana de Saúde) - BRAZIL
4) Integration of Global and Local Evidence to Improve the Implementation of Health Policies
Speaker: Jorge Otávio Maia Barreto (Fiocruz) - BRAZIL
5) Evidence-informed policies implementation: São Paulo experience
Speaker: Tereza Setsuko Toma (Secretaria de Saúde do Estado de São Paulo) - BRAZIL